The occurrence of pressure ulcers can be problematic for patients and health care systems. A medical device-related pressure ulcer (MDRPU) is considered as one of the important indicators of patient safety assessment as well as the quality of care provided to the patient. This case report concerns a 54-year-old male patient, who was admitted to the cardiac unit of a hospital. The patient developed stage II pressure ulcers due to the connection of a nonstandard probe of the electrocardiogram to its chest. Nurses had not taken any action to treat the patient’s ulcers. To improve this matter, necessary measures such as training courses should be considered by the officials and healthcare planners. Apart from this, to prevent the development of MDRPUs in the future, it is of great importance to pay special attention to the probes that are being used for the recording of an ECG.