COVID-19
Jose Luis Turabian
Abstract
Background: It's unclear whether vaccination individuals against SARS-CoV-2 protects family members in the same way. Objective: The assessment of risk factors for SARS-CoV-2 transmission from index cases with COVID-19 breakthrough infection in completely vaccinated patients to fully vaccinated family ...
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Background: It's unclear whether vaccination individuals against SARS-CoV-2 protects family members in the same way. Objective: The assessment of risk factors for SARS-CoV-2 transmission from index cases with COVID-19 breakthrough infection in completely vaccinated patients to fully vaccinated family members. Methods: From February 1 to November 30, 2021, an observational, longitudinal, and prospective research of families with one primary case of COVID-19 breakthrough infection was done in a general medicine practice in Toledo, Spain.Results: Thirteen primary cases of COVID-19 breakthrough infection in 13 families with at least one other family member were included, of which 9 were positive secondary cases (sick) and 8 were negative partners (healthy) properly vaccinated. Being a woman, being over 45 years old, being a social-health professional, being an ethnic minority, and having chronic conditions all increased the likelihood of developing COVID-19 in fully vaccinated contacts and main cases. Although vaccination 2ChAdOx1 nCoV-19 had a higher effectiveness than BNT162b2 mRNA, none of these risk or protective factors were statistically significant.Conclusion: Young women, social health workers, ethnic minority groups, and people with chronic diseases are the completely vaccinated contacts with the highest risk of having COVID-19, after primary cases also vaccinated in the family, in Toledo (Spain), when the delta variant became dominant but before the rise of omicron.
COVID-19
Sarah Cuschieri; Tamara Attard Mallia; Elaine Piscopo; Anneka Pace; Daniela Chatlani; Karl Mifsud; Nicole Mifsud; Jake Vella; Andrea Cuschieri
Abstract
Background: COVID-19 has impacted the European microstates of Andorra, Liechtenstein, Malta, Monaco, the Republic of San Marino, and Vatican City. Even though they have similar population sizes, they are rarely studied. The goal was to summarize the COVID-19 situation (January 2020–July 2021) for ...
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Background: COVID-19 has impacted the European microstates of Andorra, Liechtenstein, Malta, Monaco, the Republic of San Marino, and Vatican City. Even though they have similar population sizes, they are rarely studied. The goal was to summarize the COVID-19 situation (January 2020–July 2021) for these microstates, as well as the outcome and immunization roll-out throughout the first 18 months. While researching COVID-19 incidence and mortality trends among microstates and their land bordering nations,Methods: Epidemiological data was gathered from the database "Our World in Data," whereas COVID-19-related tactics were based on Ministry of Health webpages and local newspapers. Using COVID-19 data (where applicable), the six microstates and their adjacent nations were compared.Results: From the start of COVID-19 until August 1, 2021, the microstates reported a total of 60,174 positive cases and 730 deaths. Andorra had the greatest rates of COVID-19 infection (190 per 1,000) and mortality (1.66 per 1,000). The microstates had similar COVID-19 results, but their bordering nations shared the most striking similarities. COVID-19 cases, fatality rates, and vaccine doses all have a bidirectional link.Conclusion: Whether land borders exist, timely mitigation measures and vaccination rollouts appear to be the keys to pandemic containment. The greatest pandemic impact on a country, however, appears to be dependent on cross-border transmission rates.
COVID-19
Kyosuke Ono
Abstract
Background: A mathematical investigation of the reasons for the fifth wave's quick expansion and reduction in Tokyo, Japan, is required to avoid the spread of subsequent COVID-19 infections. Methods: Using the simple IR theory underlying the susceptible-infectious-removed (SIR) hypothesis of infectious ...
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Background: A mathematical investigation of the reasons for the fifth wave's quick expansion and reduction in Tokyo, Japan, is required to avoid the spread of subsequent COVID-19 infections. Methods: Using the simple IR theory underlying the susceptible-infectious-removed (SIR) hypothesis of infectious disease epidemics, infected persons (I), infection rate, and testing/isolation rate are determined from accessible data of daily positive cases (R) and testing numbers. Results: The rapid spread of illness from late July to mid-August was owing to a drop in the number of people tested to half that of weekdays during the Olympic Games' four and three-day vacations. The maximum number of daily positives would have been lowered to two-fifths of the actual positives in early August if the number of weekday tests had been maintained during these holidays and would have fallen monotonically thereafter. The infection rates mean value fell steadily from 0.65 in late August to around 0.25 by the end of September. The significant increase in vaccination rates is mostly to blame for the fall in infection rates. In Tokyo, the impact of mRNA-based vaccines on infection prevention and increased vaccination rates could reduce the infection rate to 1/2 on September 10 and 1/3 by the end of October. Conclusion: According to the findings, a new infection like the delta variant can be suppressed to less than the fifth wave by increasing vaccination rates, eliminating three consecutive holidays, and implementing a precautionary testing system that maintains the same number of tests on weekends as on weekdays in the event of a rapid spread of infection in an emergency.
