TY - JOUR ID - 47993 TI - Epidemiology of Kidney Stone and Bacterial Strains with Antibiotic Resistance in Shiraz, Southwest of Iran, 2014-2019 JO - International Journal of Epidemiology and Health Sciences JA - IJEHS LA - en SN - AU - Kakian, Farshad AU - Ghasemi Palangi, Mohammad AU - Hadi, Nahal AD - Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. AD - Doctor of General Medicine, Shiraz University of Medical Sciences, School of Medicine, Shiraz, Iran AD - Associate Professor of Medical Microbiology, Department of Bacteriology and Virology, School of Medicine, Shiraz University of Medical Sciences,Shiraz, Iran Y1 - 2021 PY - 2021 VL - 2 IS - Continuous SP - EP - KW - Urinary (kidney) stone KW - Epidemiology KW - Bacterial strains KW - antimicrobial resistance KW - Clinical DO - 10.51757/IJEHS.2.3.2021.47993 N2 - Background: Urinary stones are one of the major health problems worldwide and a significant part of referrals to physicians. Also, growing antibiotics resistance is an important concern. The purpose of this study was to evaluate the prevalence of urinary stones and bacterial strains with antibiotic resistance in women admitted to shiraz, southwest of Iran, from 2014 to 2019. Methods: In this period, all women admitted to the Zeinabieh Hospital were evaluated. The frequency of urinary stones and bacterial strains and antibiogram patterns of bacterial isolates were investigated from 2014 to 2019.Antibacterial susceptibility testing was done by disk diffusion method, fulfilling the standard criteria of “Clinical and Laboratory Standards Institute (CLSI) Performance Standards for Antimicrobial Susceptibility”. Results: Out of 101 isolates, the identified gram-negative bacteria were E. coli (68.3%), Klebsiella (6.9%), Enterobacter (6.9%), Pseudomonas (5%), Proteus (1%), and Acinetobacter (1%).  Of gram-positive strains, Coagulase-positive Staphylococci (5.9%), coagulase-negative Staphylococcus (CONS) (3%) and Non-Hemolytic Streptococci (2%) were identified. Also, the frequency of urinary tract stones was about 5%. Four cases of kidney stones were associated with E. coli and one case with Klebsiella. All isolates had the highest resistance to co-trimoxazole (62.5%), Ampicillin and Nalidixic acid.Conclusion: In this study, no association was found between the type of bacteria and urinary stone. From the variable bacteria isolated, the highest rate of E. coli (as an important pathogen) was confirmed.  Also, most of the bacterial isolates were resistant to multiple antibiotics, although Amikacin and nitrofurantoin (as the empirical therapy in our hospital) were dominated. UR - https://www.ijehs.com/article_47993.html L1 - https://www.ijehs.com/article_47993_9e53dfca3c774c4b94a17ab5452aec77.pdf ER -